"You're the One That I Want" is a song written by John Farrar for the 1978 film version of the musical Grease. It was performed by John Travolta and Olivia Newton-John.

The single was a huge international hit, reaching no.1 in several countries. It was the first of two songs from the Greasesoundtrack to top the U.S. and UK pop charts. It reached #1 on the U.S. Hot 100 for one week in June 1978, where it sold over 2 million copies. It also topped the UK Singles Chart for nine weeks in the summer of 1978 and, as of 2008, is still the sixth best-selling single ever in the UK where it has sold over 1,975,000 copies. A re-released version of the single reached #4 in the UK in 1998, the twentieth anniversary of the film's debut.

In 1993, Epic Records released a soundtrack album in the UK, Grease - Original London Cast Recording, and "You're the One That I Want" was recorded as a duet by Craig McLachlan and Deborah Gibson (Epic UK 659 522, released July 1993). In part due to a routine promotional push, this cover version scored big on the UK singles charts, peaking at number thirteen.

Other cover versions and appearances in other media include: