"Bad Medicine" is a number-one single by American rock band Bon Jovi. It was written by Jon Bon Jovi, Richie Sambora, and Desmond Child. It was released in 1988 as the lead single from the band's massively successful album New Jersey. The song is 5 minutes and 17 seconds long.

The song climbed to #1 on the Billboard Hot 100, #3 on the Mainstream Rock Tracks chart, #17 in the UK and #15 in Australia.

The song compares a love affair to a drug addiction ("now this boy's addicted cause your kiss is the drug", "your love is like bad medicine, bad medicine is what I need") and also has many tongue-in-cheek medical analogies ("Let's play doctor, baby cure my disease"; "There ain't no paramedic gonna save this heart attack"; "I need a respirator cause I'm runnin' out of breath").

The song is highlighted by a near constant keyboard playing by David Bryan that is well defined in the beginning of the song and at several interludes, as well as loud guitar playing by Richie Sambora, background singing in the bridge and chorus, and a loud fast-paced delivery of lyrics by Jon Bon Jovi. It is one of the more upbeat and hard rocking songs on New Jersey.

Towards the end of the song, Jon says he's got to go and he's running out of breath, but then says "I'm not done...one more time, with feelin'" and the band finishes out the song with another repeat of the chorus.

There are two videos for the song, one with the band live in concert, and the more well-known live video in which a crowd of young people waiting in line to get into the Bon Jovi live video shoot is asked by Sam Kinison if they (the public) "can make a better Bon Jovi video than these guys can." The crowd gives a very enthusiastic response, and members of the crowd are given hand-held cameras and invited onstage to help shoot the video.

The video was very groundbreaking at the time for using such a fan-inclusive approach to making a music video, and captured live shots not often captured by regular video crews.

The video was in color, although the quality given by the hand-held video cameras was not as superb.,

"Bad Medicine" continues to see considerable airplay on many rock radio stations and has always been a live staple at Bon Jovi concerts. In concert, an approximately 1-minute interlude of the classic "Shout" is incorporated into the middle of the song.

The song was featured on the band's compilation album Cross Road, the live album One Wild Night: Live 1985-2001, the acoustic collection This Left Feels Right, as well as several concert videos including Live From Londonand The Crush Tour.

The song was covered by the post-punk band Allah & The 72 Virgins on their 2002 album Name Me With My Title.