"Money Maker" is the first single from Ludacris's fifth album Release Therapy. The song was released to the radio on July 17, 2006. The song is produced by The Neptunes and features Pharrell. The song was written by Chris Bridges (Ludacris), and Pharrell Williams. The video was released on August 17, 2006. The video premiered on MTV's Making the Video. The single reached number 1 on various charts. It has peaked at number 1 on the Billboard Hot 100, the Hot R&B/Hip-Hop Songs, and number 1 on Hot Rap Tracks in the United States. It also became the number 1 single on radio in the United States on October 19, 2006. The music video managed to enter BET's 106 & Park and peak at number 1, where it remained for several days. The single has strong airplay on BET and MTV. It also has airplay on Canada's Muchmusic. The single has a major promotional status and huge airplay on radio around the U.S., North America and other countries around the globe. The song was performed on the 2006 MTV Video Music Awards. This is Ludacris's third #1 hit single.

American R&B singer, Amerie, also recorded an answer back (remix) to the single. The song was included on her first Mixtape, Because I Love It Volume 1(the mixtape that was released to accompany her third studio Because I Love It), but didn't appear on the album, that was never released in the United States.

The song won a Grammy Award for Best Rap Song in 2007.

The "Money Maker" video was released August 17, 2006. It premiered on various channels including BET, MTV, and MuchMusic in that week.

The video to "Money Maker" is a simple video. It is basically coloured backgrounds of orange, green and black throughout the shots. There are shots of Ludacris on the ground rapping with girls surrounding him. Pharrell is also singing the chorus around girls on stacks of money. Ludacris has a counting machine that counts how many times he has got a girl to shake her money maker (buttocks) for him - a reference to a commercial featuring himself using the same kind of device to click off the amount of women who flirt with him in his everyday life. Girls are also dancing throughout the video. "Money Maker" was shot by director Melina, who directed Shareefa's Need a Boss.

The video is noteworthy in that is was Ludacris' first appearance on camera with his newly-cut hair, as Ludacris had cut his trademark cornrows in order to signify a new image for the rapper.

The large speakers in the background vibrating throughout the video are no more than salad bowls, according to Ludacris in MTV's "Making the Video."

The video also features a Chrysler ME Four-Twelve.

Cameo appearances are made by Allen Iverson, Shareefa, Bobby Valentino, & Lil Fate.