"Save the Last Dance for Me" is the title of a popular song written by Doc Pomus and Mort Shuman, first recorded in 1960 by Ben E. King with The Drifters.

The Drifters' version of the song spent three non-consecutive weeks at number one on the U.S. pop chart, in addition to logging one week atop the U.S. R&B chart. In the UK, the Drifters' recording reached number two in December 1960. This single was produced by Jerry Leiber and Mike Stoller, two noted American music producers who at the time had an apprentice relationship with a then-unknown Phil Spector. Although he was working with Lieber and Stoller at the time, it is unknown whether Spector assisted with the production of this record; however, many Spector fans have noticed similarities between this record and other music he would eventually produce on his own.

In the song, the narrator tells his lover she is free to mingle and socialize throughout the evening, but to make sure to save him one dance at the end of the night. The song is likely based on the personal experience of songwriter Pomus, who had polio and used crutches to get around and could not dance. His wife, however, was a Broadway actress and dancer. The song gives his perspective of plaintively telling his wife to have fun dancing, but reminds her who will be taking her home and "in whose arms you're gonna be." The personnel for the Drifters' recording were: Bucky Pizzarelli, Allan Hanlon (guitar), Lloyd Trotman (bass), Gary Chester (drums).

"Save the Last Dance for Me" was the second, and last, single to be released from It's Time, Michael Bublé's second album. This version of the song first made the American music charts as a dance recording that was listed as being remixed by "Ralphi Rosario and Eddie Baez". The remixes peaked at #22 on the Billboarddance chart in September 2005. In early 2006, the album version of the song was released to radio, and it peaked at number five on the Billboardadult contemporary chart as well as reaching number 99 on the Hot 100 chart. Bublé sings the song at the end of the 2005 film The Wedding Date.